Services

mTOR/Pi3 kinase Pathway

mTOR/Pi3 kinase Pathway Genes

mTOR/Pi3 kinase genes involved in Apoptosis:

AKT1, APC ,BAD, BTK, CASP9, CD14, CDKN1B, CTNNB1, EIF2AK2, FASLG, FOXO1, FOXO3, GSK3B, HRAS, HSPB1, IGF1, IGF1R, ILK, IRAK1, JUN, MAPK1, MAPK8, MYD88, NFKB1, NFKBIA, PAK1, PIK3CA, PIK3CG, PIK3R2, PRKCA, PRKCZ, PTEN, RAC1, RAF1, RASA1, RHOA, SOS1, TLR4

mTOR/Pi3 kinase genes involved in Cell Differentiation:

AKT1, APC, BAD, CCND1, CTNNB1, GRB2, HRAS, IGF1, ITGB1, JUN, MAP2K1, MAPK1, NFKB1, NFKBIA, RHOA, RPS6KB1, SRF, TSC1

mTOR/Pi3 kinase genes involved in Cell Proliferation:

AKT1, APC, BAD, CCND1, CDKN1B, CTNNB1, FOXO1, HRAS, IGF1, IGF1R, ILK, IRS1, JUN, MAP2K1, MAPK1, MAPK3, MTCP1, NFKBIA, PRKCA, PRKCZ, PTEN, RAF1, RBL2, RPS6KB1, SHC1, TSC1, TSC2

mTOR/Pi3 kinase genes involved in other roles:

ACTB, ADAR, AKT2, AKT3, B2M, CDC42, CHUK, CSNK2A1, EIF4B, EIF4E, EIF4EBP1, EIF4G1, ELK1, FKBP1A, FOS, GAPDH, GJA1, GRB10, HPRT1, MAPK14, PABPC1, PDGFRA, PDK1, PDK2, PDPK1, PIK3R1, PRKCB, PTK2, PTPN11, RHEB, RPL13A, RPS6KA1, TCL1A, TIRAP, TOLLIP, WASL, YWHAH

Assessments we can conduct

1. Microarray Assessments:

• Custom Arrays containing multiple probe sets for all specified genes or pathways of interest
• Optional inclusion of the entire human, mouse or rat genome

2. qPCR analysis:

• Any specified genes or pathways of interest
• Each primer set designed and QC'ed by Epistem

3. Information from our proprietary PathwayDirect™ database containing extensive information on samples analysed by Epistem.

To obtain more information on monitoring genes in the mTOR/Pi3 kinase pathway, please click here.

Microarray Analysis

Custom Array Analysis on any specified genes or pathways of interest. Optional inclusion of the entire genome.

qPCR Analysis

Any specified genes or pathways of interest.