Services

cMET Signalling Pathway

Genes we can monitor in the cMET Pathway

cMET Signalling Genes involved in Apoptosis:

DOCK1, HGF, HRAS, ITGA1, JUN, MAPK1, MAPK8, PAK1, PIK3CA, PTEN, PTK2B, RAF1, RASA1, SOS1

cMET Signalling Genes involved in Cell Differentiation:

GLMN, GRB2, HRAS, INHBB, ITGB1, JUN, MAP2K1, MAPK1, PTK2B, STAT3

cMET Signalling Genes involved in Cell Proliferation:

ACTA1, GAB1, GLMN, HRAS, JUN, MAP2K1, MAPK1, MAPK3, MET, PTEN, PTK2B, RAF1, RAP1B

cMET Signalling Genes involved in other roles:

CRK, CRKL, ELK1, FOS, MAP2K2, MAP4K1, PIK3R1, PTK2, PTPN11, PXN, RAP1A, SRC

Assessments we can conduct

1. Microarray Assessments:

• Custom Arrays containing multiple probe sets for all specified genes or pathways of interest
• Optional inclusion of the entire human, mouse or rat genome

2. qPCR analysis:

• Any specified genes or pathways of interest
• Each primer set designed and QC'ed by Epistem

3. Information from our proprietary PathwayDirect™ database containing extensive information on samples analysed by Epistem.

To obtain more information on monitoring genes within the cMET signalling pathway, please click here.

Microarray Analysis

Custom Array Analysis on any specified genes or pathways of interest. Optional inclusion of the entire genome.

qPCR Analysis

Any specified genes or pathways of interest.